Cortex XDR is listed under EDR and XDR by Palo Alto Networks. The 12 alternatives below are listed in the same category and are compared on starting price, features and reviews from other MSPs.
Updated .
SentinelOne Autonomous endpoint detection and response with one-click rollback, per-endpoint annual pricing. Cortex XDR vs SentinelOne
Trend Vision One Endpoint Security Endpoint protection with EDR, XDR and threat hunting under credit-based licensing. 
FortiEDR Endpoint detection and response integrated with the Fortinet Security Fabric, quote-only pricing. 
ESET PROTECT Prevention-focused endpoint detection and response with cloud or on-premises deployment. 
Cynet Unified Unified endpoint and network security with 24/7 managed response, priced per endpoint per month. 
CrowdStrike Falcon Cloud-native EDR with behavioral detection, threat hunting and managed response via OverWatch. Cortex XDR vs CrowdStrike Falcon
Sophos Endpoint AI-powered EDR with behavioural detection and ransomware rollback on Windows, macOS and Linux. 
Microsoft Defender for Endpoint Enterprise EDR bundled with Microsoft 365 E5, with multi-tenant management for MSPs via Lighthouse. Cortex XDR vs Microsoft Defender for Endpoint
Coro A consolidated SMB and MSP cybersecurity platform sold via partners on quote-only, per-user pricing. 
Bitdefender GravityZone Unified EDR, XDR and MDR in one cloud console with consumption-based MSP pricing. 
Huntress Managed detection and response for MSPs, priced per endpoint from $7.99 a month direct. Cortex XDR vs Huntress| Feature | Cortex XDR | SentinelOne | Trend Vision One Endpoint Security | FortiEDR | ESET PROTECT | Cynet Unified | CrowdStrike Falcon |
|---|---|---|---|---|---|---|---|
| Behavioural detection | yes | yes | yes | yes | yes | yes | yes |
| Automated remediation | yes | yes | yes | yes | yes | yes | yes |
| Rollback to pre-attack state | yes | yes | yes | yes | yes | yes | unknown |
| USB and device control | yes | yes | yes | yes | yes | yes | yes |
| Application allow-listing | yes | yes | yes | yes | unknown | yes | yes |
| Offline protection | yes | yes | yes | unknown | yes | yes | unknown |
| Threat hunting console | yes | yes | yes | yes | yes | yes | yes |
| Managed MDR add-on | yes | yes | yes | yes | yes | yes | yes |
| SIEM and SOAR integration | yes | yes | yes | yes | yes | yes | yes |
| RMM integration | unknown | yes | yes | unknown | yes | yes | yes |
| macOS support | yes | yes | yes | yes | yes | unknown | yes |
| Linux support | yes | yes | yes | yes | yes | yes | yes |
SentinelOne, which matches 11 of the 11 features Cortex XDR supports.
