Microsoft Defender for Business alternatives for MSPs

Microsoft Defender for Business is listed under EDR and XDR by Microsoft. The 4 alternatives below are listed in the same category and are compared on starting price, features and reviews from other MSPs.

Updated 5 September 2026.

1. Blackpoint Cyber MDR built around a proprietary SOC platform and a 24-hour analyst team.
   No reviews yet

   Blackpoint Cyber · cloud

2. Huntress Managed EDR with a human-staffed SOC built specifically for MSPs.
   No reviews yet

   Huntress · cloud

3. SentinelOne AI-driven EDR and XDR with autonomous, one-click threat rollback.
   No reviews yet

   SentinelOne · cloud

4. ThreatLocker Default-deny application control and ringfencing to stop what has not been approved.
   No reviews yet

   ThreatLocker · cloud

Features

Features compared

Feature	Microsoft Defender for Business	Blackpoint Cyber	Huntress	SentinelOne	ThreatLocker
Behavioural detection	unknown	unknown	unknown	yes	no
Automated remediation	yes	unknown	unknown	yes	no
Rollback to pre-attack state	unknown	unknown	unknown	yes	no
USB and device control	unknown	unknown	unknown	unknown	unknown
Application allow-listing	yes	unknown	unknown	unknown	yes
Offline protection	unknown	unknown	unknown	yes	unknown
Threat hunting console	unknown	unknown	unknown	unknown	unknown
Managed MDR add-on	unknown	unknown	unknown	yes	unknown
SIEM and SOAR integration	unknown	unknown	unknown	yes	unknown
RMM integration	no	unknown	unknown	unknown	yes
macOS support	unknown	unknown	unknown	unknown	unknown
Linux support	unknown	unknown	unknown	unknown	unknown

Related pages

Microsoft Defender for Business listing All EDR and XDR software Blackpoint Cyber alternativesHuntress alternativesSentinelOne alternativesThreatLocker alternatives