ThreatLocker alternatives for MSPs

ThreatLocker is listed under EDR and XDR by ThreatLocker. The 4 alternatives below are listed in the same category and are compared on starting price, features and reviews from other MSPs.

Updated 5 September 2026.

1. Blackpoint Cyber MDR built around a proprietary SOC platform and a 24-hour analyst team.
   No reviews yet

   Blackpoint Cyber · cloud · Matches 0 of 2 features ThreatLocker supports

2. Huntress Managed EDR with a human-staffed SOC built specifically for MSPs.
   No reviews yet

   Huntress · cloud · Matches 0 of 2 features ThreatLocker supports

3. SentinelOne AI-driven EDR and XDR with autonomous, one-click threat rollback.
   No reviews yet

   SentinelOne · cloud · Matches 0 of 2 features ThreatLocker supports

4. Microsoft Defender for Business Endpoint protection built into the Microsoft 365 Business Premium licence.
   No reviews yet

   Microsoft · cloud

Features

Features compared

Feature	ThreatLocker	Blackpoint Cyber	Huntress	SentinelOne	Microsoft Defender for Business
Behavioural detection	no	unknown	unknown	yes	unknown
Automated remediation	no	unknown	unknown	yes	yes
Rollback to pre-attack state	no	unknown	unknown	yes	unknown
USB and device control	unknown	unknown	unknown	unknown	unknown
Application allow-listing	yes	unknown	unknown	unknown	yes
Offline protection	unknown	unknown	unknown	yes	unknown
Threat hunting console	unknown	unknown	unknown	unknown	unknown
Managed MDR add-on	unknown	unknown	unknown	yes	unknown
SIEM and SOAR integration	unknown	unknown	unknown	yes	unknown
RMM integration	yes	unknown	unknown	unknown	no
macOS support	unknown	unknown	unknown	unknown	unknown
Linux support	unknown	unknown	unknown	unknown	unknown

Related pages

ThreatLocker listing All EDR and XDR software Blackpoint Cyber alternativesHuntress alternativesSentinelOne alternativesMicrosoft Defender for Business alternatives